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    Complimentary Article

    Dermal wipe sampling method development and validation for semivolatile and nonvolatile flame-retardant compounds TBBPA and TPP for use in occupational exposure assessments

    Coauthored by Lauren Gloekler, MEM of Roux

    This article describes the laboratory development and validation of a method to identify and quantify the semivolatile organic compounds, tetrabromobisphenol A (TBBPA, CAS: 79-94-7) and triphenyl phosphate (TPP, CAS: 115-86-6) in dermal wipe samples and to validate recovery of these chemicals from porcine skin. The analytical method involved extraction of the test compounds on two different wipe media (cotton and polyester-rayon blend) in 100% isopropanol using gas chromatography-mass spectrometry.

    This study provides a framework to perform validation of analytical and dermal sample collection methods for other semivolatile and nonvolatile chemicals and provides a baseline method for the development of commercial laboratory methods to evaluate exposure to other chemicals.

    This research article is published by the Journal of Occupational and Environmental Hygiene. To access the article, please complete the form.